Thursday 9 March 18:00 - 19:30

Blizard Institute
4 Newark Street
E1 2AT

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The 100,000 Genomes Project - how did it change healthcare?

Science & Technology

Ever wondered what a genome is? Or how it relates to people's health?

Prof. Sir Mark Caulfield will be answering these questions and more in his free Big Question lecture.

Event details

Format: 45 minute lecture with time for a Q&A, followed by refreshments in the Blizard Institute reception

Tickets for the lecture are free of charge, but booking is essential. Over 14s only. Walk ins will also be accepted if there is extra space on the night.

For enquiries about the lecture please contact Myfanwy-Cerys Williams on [email protected] For any enquiries about Centre of the Cell, contact our Bookings Officer, Mohammed Rofik, on 0207 882 2562. Visitor information about Centre of the Cell can be found at

What is a Big Question lecture?

Centre of the Cell’s Big Question Lectures are brought to you by top scientists at Queen Mary University of London, in partnership with Centre of the Cell and co-created with young people from our Youth Membership Scheme. They give audiences from age 14 the chance to hear from leaders in science and healthcare about the cutting-edge biology and innovative front-line medicine going on right here in east London.

The speaker

Professor Sir Mark Caulfield is Professor of Clinical Pharmacology at Queen Mary University of London and the Vice Principal for Health for Queen Mary’s Faculty of Medicine and Dentistry.

Professor Caulfield graduated in Medicine in 1984 from the London Hospital Medical College and trained in Clinical Pharmacology at St Bartholomew’s Hospital where he developed a research programme in molecular genetics of hypertension and translational clinical research.

At Queen Mary University of London Professor Caulfield has made substantial contributions to the discovery of genes related to blood pressure, cardiovascular health, cancer and rare diseases. His research has changed national and international guidance for high blood pressure. He was Director of Queen Mary’s William Harvey Research Institute between 2002-2020 and was elected to the Academy of Medical Sciences in 2008.

He has won the Lily Prize of the British Pharmacology Society, the Bjorn Folkow Award of the European Society of Hypertension 2016 and the Franz Volhard Award of the International Society of Hypertension in 2018.

Professor Caulfield was appointed Chief Scientist for Genomics England in 2013, charged with delivery of the 100,000 Genomes Project on whole genome sequencing in rare disease, cancer and infection. At Genomics England, he was instrumental in delivering the 100,000 Genomes Project which has delivered life-changing results for many patients. He has also worked with NHS England to co-create the National Genomic Test Directory, which offers equitable access for 56 million people to appropriate genomic tests. Professor Caulfield was awarded a knighthood in 2019 for his leadership of the 100,000 Genomes Project.

He is a member of the Barts Health NHS Trust Board, the Barking, Havering and Redbridge University Hospitals NHS Trust, the MedCity Board and is the President Elect of the British Pharmacological Society.

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